TheRetroArcade
Veteran
Posts: 1,961
Joined: Feb 2026
Joined: Feb 2026
Take three steps to the left when you hear the bird sing twice after midday.
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Throughout my playthrough of Resident Evil Requiem, I came across a few items which I had absolutely no clue what to do with. I investigated some further, but didn't dwell on it; I had a review to write after all. But after getting to the end, a checkbox for The Final Puzzle popped up in the challenges menu. Great, now I'm even more confused.
After endless discussions with PC Gamer's senior guides writer Sean Martin and a helpful peep at IGN's The Final Puzzle reveal, we've finally gotten to the bottom of what all these extra items were for. Well, most of them.
Spoiler warning for Resident Evil Requiem puzzle solutions and story elements ahead
It's just as convoluted as we feared. Towards the end of Rhodes Hill Hospital, you'll find a weird and gory item called the Severed Hand. Ok. What does this do? Well, if you put it under one of the laser microscopes you can find around Rhodes Hill, it'll reveal the following: GGC AAG AUA UGU CAU, along with this message: "Let's play." No, I don't think I will.
The string of letters is actually a DNA sequence. You get to keep the hand even after you've analysed it, so I just thought it was an easter egg at first. Resident Evil deals with a lot of infectious viruses and mutations, after all. But no, it's actually the start of something way bigger than I could've imagined.
There are several stages you need to complete throughout the course of the rest of Resident Evil Requiem, which'll then land you with the prize of ticking off The Final Puzzle checklist. But here's the kicker: no one seems to have been able to solve this puzzle yet, including us.
The trick seems to be finding out which of the following symbols: Moon, Star, and Sun, correspond to the letters in the DNA sequence. I spent about five minutes turning an hourglass around in Grace's hands while in Gideon's secret lab, before shoving it back in my inventory, never to be used again. But now I discover it has a secret code written into its base, which you can only see if you hold it upside down and wait for the sand to fall away.
Keep up to date with the most important stories and the best deals, as picked by the PC Gamer team.
The code on the hourglass reads "U = 380,000", which apparently means Moon, as this is 380,000km away from Earth (obviously). A note you find ...Read more: Full article on www.pcgamer.com
What do you think about this?
When you purchase through links on our site, we may earn an affiliate commission. Here’s how it works.
Keep up to date with the most important stories and the best deals, as picked by the PC Gamer team.
You are now subscribed
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Every Friday
GamesRadar+
Your weekly update on everything you could ever want to know about the games you already love, games we know you're going to love in the near future, and tales from the communities that surround them.
Every Thursday
GTA 6 O'clock
Our special GTA 6 newsletter, with breaking news, insider info, and rumor analysis from the award-winning GTA 6 O'clock experts.
Every Friday
Knowledge
From the creators of Edge: A weekly videogame industry newsletter with analysis from expert writers, guidance from professionals, and insight into what's on the horizon.
Every Thursday
The Setup
Hardware nerds unite, sign up to our free tech newsletter for a weekly digest of the hottest new tech, the latest gadgets on the test bench, and much more.
Every Wednesday
Switch 2 Spotlight
Sign up to our new Switch 2 newsletter, where we bring you the latest talking points on Nintendo's new console each week, bring you up to date on the news, and recommend what games to play.
Every Saturday
The Watchlist
Subscribe for a weekly digest of the movie and TV news that matters, direct to your inbox. From first-look trailers, interviews, reviews and explainers, we've got you covered.
Once a month
SFX
Get sneak previews, exclusive competitions and details of special events each month!
Throughout my playthrough of Resident Evil Requiem, I came across a few items which I had absolutely no clue what to do with. I investigated some further, but didn't dwell on it; I had a review to write after all. But after getting to the end, a checkbox for The Final Puzzle popped up in the challenges menu. Great, now I'm even more confused.
After endless discussions with PC Gamer's senior guides writer Sean Martin and a helpful peep at IGN's The Final Puzzle reveal, we've finally gotten to the bottom of what all these extra items were for. Well, most of them.
Spoiler warning for Resident Evil Requiem puzzle solutions and story elements ahead
It's just as convoluted as we feared. Towards the end of Rhodes Hill Hospital, you'll find a weird and gory item called the Severed Hand. Ok. What does this do? Well, if you put it under one of the laser microscopes you can find around Rhodes Hill, it'll reveal the following: GGC AAG AUA UGU CAU, along with this message: "Let's play." No, I don't think I will.
The string of letters is actually a DNA sequence. You get to keep the hand even after you've analysed it, so I just thought it was an easter egg at first. Resident Evil deals with a lot of infectious viruses and mutations, after all. But no, it's actually the start of something way bigger than I could've imagined.
There are several stages you need to complete throughout the course of the rest of Resident Evil Requiem, which'll then land you with the prize of ticking off The Final Puzzle checklist. But here's the kicker: no one seems to have been able to solve this puzzle yet, including us.
The trick seems to be finding out which of the following symbols: Moon, Star, and Sun, correspond to the letters in the DNA sequence. I spent about five minutes turning an hourglass around in Grace's hands while in Gideon's secret lab, before shoving it back in my inventory, never to be used again. But now I discover it has a secret code written into its base, which you can only see if you hold it upside down and wait for the sand to fall away.
Keep up to date with the most important stories and the best deals, as picked by the PC Gamer team.
The code on the hourglass reads "U = 380,000", which apparently means Moon, as this is 380,000km away from Earth (obviously). A note you find ...Read more: Full article on www.pcgamer.com
What do you think about this?